Senator Selina Meyer has just become the Vice President of the United States...and discovered that the job is nothing like she expected--but everything she was warned about. Season one follows the whirlwind day-to-day existence of Vice President Meyer as she puts out political fires, juggles public and private demands and defends the interests of the chief executive--with whom she shares a uniquely dysfunctional relationship.

In season two, Selina tries to parlay slightly above average popularity polls into increased influence with the president and his new senior strategist Kent Davison. But just as in the first season, even the most banal decision made by Selina and her staff can have the most unexpected and far-reaching consequences.

After the revelation at the end of Season 2 that the president will not run for re-election, Season 3 begins with Selina, eyeing a promotion, courting Iowa Caucus voters at a signing of her new book. Soon, however, she learns that the Secretary of Defense, war veteran Danny Chung, is resigning - setting the stage for a possible clash with her nemesis in the presidential primaries.

In season four, POTUS is stepping down and newly sworn-in President Selina Meyer scrambles to hang on to her new office while avoiding becoming America's shortest-serving president. While Selina has ascended to the highest office in the land, she must still run for election, prompting her and her staff to grapple with making her seem “presidential” while also deciding who will make the best running mate.

In season five, Amy and Dan are on the ground in Nevada working on a recount, and Selina finds herself spinning her wheels in DC, as her staff continues their mission to make her seem presidential (even though she is the President) while fending off the ambitions of her charismatic Vice Presidential running mate Tom James, who in a twist of obscure constitutional procedure could end up becoming President.

In season six, former Vice President and onetime President Selina Meyer looks to secure her legacy now that she's out of office.

Selina Meyer, the former vice president and president, is looking to get back to the Oval Office. Can she shake off years of flubs and scandals?